LONGEVITY CLUB: BERBERINE 500
Berberine Hydrochloride: 500 mg per serving.
As a dietary supplement, adults take 1 (one) capsule, three times per day.
General Information and Actions:
Provides support for healthy glucose metabolism. Helps support healthy blood lipid levels. Helps support healthy cholesterol levels (serum triglyceride, total, and LDL).
Helps support cardiovascular health.
Cautions and Warnings:
If you have hypoglycemia, hypotension, a liver or kidney disorder, cardiovascular disease, diabetes, gall stones or a blood disorder, consult your health care professional before use.
Consult a health care practitioner prior to use if you are taking other medications or natural health products.
Do not use if you are pregnant, breastfeeding, or if you have scleroderma.
Known adverse reactions:
Gastrointestinal discomfort (i.e., diarrhea, vomiting, nausea, abdominal pain, or constipation) has been known to occur; in which case, discontinue use and consult a health care practitioner.
1.Yueshan Hu et al., Lipid-lowering effect of berberine in human subjects and rats, Phytomedicine 19 (2012) 861– 867
2.Hao Zang et al., Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression, Metabolism Clinical and Experimental 59 (2010) 285–292
3.Zhao et al. , Efficacy and safety of berberine for dyslipidemia: study protocol for a randomized double-blind placebo-controlled trial, Trials, (2021) 22:85
4.Pérez-Rubio KG, González-Ortiz M, Martínez-Abundis E, Robles-Cervantes JA, Espinel-Bermúdez MC. Metab Syndr Relat Disord. 2013 Oct;11(5):366-9. doi: 10.1089/met.2012.0183. Epub 2013 Jun 28.
5.Jin Y, Khadka D, Cho WC. Pharmacological effects of berberine and its derivatives: a patent update. Expert Opin Ther Pat. 2016;26(2):229-243.